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BMJ No 7099 Volume 315

Papers - Abstracts Saturday 5 July 1997


Dietary pattern and 20 year mortality in elderly men in Finland, Italy, and the Netherlands: longitudinal cohort study
Physiotherapy for patients with soft tissue shoulder disorders: a systematic review of randomised clinical trialsoking related diseases
Incidence and outcome of bleeding before the 20th week of pregnancy: prospective study from general practice


Dietary pattern and 20 year mortality in elderly men in Finland, Italy, and the Netherlands: longitudinal cohort study

Patricia Huijbregts, Edith Feskens, Leena Räsänen, Flaminio Fidanza, Aulikki Nissinen, Alessandro Menotti, Daan Kromhout

Abstract

Objective: To investigate the association of dietary pattern and mortality in international data.

Design: Cohort study with 20 years' follow up of mortality.

Setting: Five cohorts in Finland, the Netherlands, and Italy.

Subjects: Population based random sample of 3045 men aged 50-70 years in 1970.

Main outcome measures: Food intake was estimated using a cross check dietary history. In this dietary survey method, the usual food consumption pattern in the 6-12 months is estimated. A healthy diet indicator was calculated for the dietary pattern, using the World Health Organisation's guidelines for the prevention of chronic diseases. Vital status was verified after 20 years of follow up, and death rates were calculated.

Results: Dietary intake varied greatly in 1970 between the three countries. In Finland and the Netherlands the intake of saturated fatty acids and cholesterol was high and the intake of alcohol was low; in Italy the opposite was observed. In total 1796 men (59%) died during 20 years of follow up. The healthy diet indicator was inversely associated with mortality (P for trend <0.05). After adjustment for age, smoking, and alcohol consumption, the relative risk in the group with the healthiest diet indicator compared with the group with the least healthy was 0.87 (95% confidence interval 0.77 to 0.98). Estimated relative risks were essentially similar within each country.

Conclusions: Dietary intake of men aged 50-70 is associated with a 20 year, all cause mortality in different cultures. The healthy diet indicator is useful in evaluating the relation of mortality to dietary patterns.

Department of Chronic Diseases and Environmental Epidemiology,
National Institute of Public Health and the Environment,
PO Box 1,
NL-3720 BA Bilthoven,
Netherlands
Patricia Huijbregts, research fellow
Edith Feskens, senior epidemiologist
Daan Kromhout, professor of public health research

Division of Nutrition,
Department of Applied Chemistry and Microbiology,
University of Helsinki,
00014 Helsinki,
Finland
Leena Räsänen, assistant professor of nutrition

Institute of Food Sciences and Nutrition,
University of Perugia,
Perugia,
00610
Italy
Flaminio Fidanza, professor of nutrition

Department of Community Health and General Practice,
University of Kuopio,
70211 Kuopio,
Finland
Aulikki Nissinen, professor of community health and general practice

Division of Epidemiology,
School of Public Health,
University of Minnesota,
Minneapolis,
MN 55454-1015,
USA
Alessandro Menotti, professor of epidemiology

Correspondence to: Ms Huijbregts.


Physiotherapy for patients with soft tissue shoulder disorders: a systematic review of randomised clinical trials

Geert J M G van der Heijden, Daniëlle A W M van der Windt, Andrea F de Winter

Abstract

Objective: To assess the effectiveness of physiotherapy for patients with soft tissue shoulder disorders.

Design: A systematic computerised literature search of Medline and Embase, supplemented with citation tracking, for relevant trials with random allocation published before 1996.

Subjects: Patients treated with physiotherapy for disorders of soft tissue of the shoulder.

Main outcome measures: Success rates, mobility, pain, functional status.

Results: Six of the 20 assessed trials satisfied at least five of eight validity criteria. Assessment of methods was often hampered by insufficient information on various validity criteria, and trials were often flawed by lack of blinding, high proportions of withdrawals from treatment, and high proportions of missing values. Trial sizes were small: only six trials included intervention groups of more than 25 patients. Ultrasound therapy, evaluated in six trials, was not shown to be effective. Four other trials favoured physiotherapy (laser therapy or manipulation), but the validity of their methods was unsatisfactory.

Conclusions: There is evidence that ultrasound therapy is ineffective in the treatment of soft tissue shoulder disorders. Due to small trial sizes and unsatisfactory methods, evidence for the effectiveness of other methods of physiotherapy is inconclusive. For all methods of treatment, trials were too heterogeneous with respect to included patients, index and reference treatments, and follow up to merit valid statistical pooling. Future studies should show whether physiotherapy is superior to treatment with drugs, steroid injections, or a wait and see policy.

Institute for Rehabilitation Research,
PO Box 192,
6430 AD Hoensbroek,
Netherlands
Geert J M G van der Heijden, senior researcher

Institute for Research in Extramural Medicine,
Vrije Universiteit,
Amsterdam,
Netherlands
Daniëlle A W M van der Windt, research fellow
Andrea F de Winter, research fellow

Correspondence to: Dr van der Heijden.


Incidence and outcome of bleeding before the 20th week of pregnancy: prospective study from general practice

Christopher Everett

Abstract

Objective: To estimate the miscarriage rate in a cohort of pregnant women and the final outcome of pregnancy.

Design: Two year prospective community study.

Setting: Women registered with four semirural practices at one health centre.

Subjects: 626 pregnant women from a population 21,448, 5,140 of whom were women aged 15-44 years.

Main outcome measures: Vaginal bleeding and outcome of pregnancy.

Results: 76 of the 89 women with an unwanted pregnancy requested a termination. In the 550 ongoing pregnancies bleeding occurred before the 20th week in 117 (21%), and 67 (12%) ended in miscarriage. The risk of miscarriage was not significantly increased after a miscarriage in the previous pregnancy (11 (15%) women had miscarriage v 55 (12%) women who had not had miscarriage) who had previously had a live birth). Of the 117 women with bleeding, 64 were not admitted to hospital by the general practitioner; 42 of these women had an ultrasound examination at the health centre and 19 subsequently miscarried at home. In hospital 41 of 46 women who miscarried had evacuation of the uterus.

Conclusions: Bleeding occurred in one fifth of recognised pregnancies before the 20th week and over half of these miscarried. Treatment of women with miscarriage at home means current statistics on miscarriage in Britain are missing many cases.

Alton Health Centre,
Alton,
Hampshire GU34 2QX
Christopher Everett, general practitioner

Correspondence to: Church Cottage,
Holybourne,
Alton,
Hampshire GU34 4HD.


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