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BMJ No 7098 Volume 314

This week in BMJ Saturday 21 June 1997


Benefits of corticosteroid treatment in head injury are still uncertain
Switching from cigarettes to cigars or pipes benefits health
Placental weight to birthweight ratio: just a surrogate marker?
Reliability of public oriented healthcare information on the internet is poor

Benefits of corticosteroid treatment in head injury are still uncertain

Corticosteroids have been used for over 30 years in the treatment of head injury, though several randomised controlled trials have produced apparently conflicting findings. This uncertainty is reflected in substantial variation in the use of corticosteroids. On p 1855 Alderson and Roberts present a systematic review of such trials which confirms continuing uncertainty over the effects of corticosteroids; neither moderate benefit nor moderate harm can be excluded. This situation can be resolved only by further large scale randomised trials.

Switching from cigarettes to cigars or pipes benefits health

The risk of smoking related diseases is lower in men who smoke pipes and cigars than in men who smoke cigarettes. The best advice for a cigarette smoker is to stop smoking, but not everyone is able to stop. Should such people be advised to switch to pipes or cigars? The results of the study by Wald and Watt on p 1860 show that the answer is yes: such a switch will roughly halve the risk of dying of these diseases. This prospective study of 21,520 men also showed that most of this benefit is achieved through simply smoking less tobacco; though some comes from reduced inhaling.

Placental weight to birthweight ratio: just a surrogate marker?

The relative weights of the infant and the placenta at delivery are important predictors of adult disease, particularly hypertension. Williams et al (p 1864) determined the demographic, environmental, and medical factors which influence the relative weights of the newborn infant and the placenta and compared this ratio with other factors known to predispose to ill health. They conducted a prospective cohort study of 2,507 pregnant women who delivered a single live infant at term. Significant correlations were observed between the placental weight to birthweight ratio and various known risk factors for adult hypertension, suggesting that the ratio may be a surrogate for biological and environmental factors which may act before or after birth. No consistent correlations were observed between the placental weight to birthweight ratio and measures of newborn size, so the ratio may not be a good marker of fetal growth when used in retrospective studies.

Reliability of public oriented healthcare information on the internet is poor

To assess the reliability of healthcare information on the world wide web and how it may help lay people cope with common health problems, Impicciatore et al (p 1875) made a systematic search of web pages dealing with the home management of childhood fever. There was a wide variety in both the type of information contained and the quality with which it was organised and presented. Only four of the 41 web pages retrieved gave the same main advice as the published guidelines chosen as the standard.


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