Letter
Vitamin D deficiency
More evidence is needed before general supplementation
Cite this as:
BMJ
2008;336:1451.1
- Miles D Witham, clinician scientist, ageing and health
- 1University of Dundee, Ninewells Hospital, Dundee DD1 9SY
Holick is right to highlight the high prevalence of vitamin D insufficiency in many groups of people living at higher latitudes.1 However, the evidence base to support general supplementation, including aggressive fortification, does not currently exist.
An impressive array of observational data suggests that low vitamin D concentrations are associated with a wide variety of diseases, including diabetes, cardiovascular disease, and cancer. …
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