Arrowsmith has a claim to be the greatest ever novel about medical research. Writing at the very beginning of a revolution in medicine that would yield a generation of powerful drugs, Sinclair Lewis evokes the past, present, and future of the profession, all through the career of Dr Martin Arrowsmith. Informed by Lewis's friend, the ex-Rockefeller Institute scientist Paul De Kruif, the book is based on real characters and actual institutions. It is a cutting satire, but beneath the wit is a powerful call to recognise science as the source of both truth and health. Numerous scientists …