- David L Sackett, trialist (sackett@bmts.com)
- Trout Research and Education Centre at Irish Lake, RR 1, Markdale, ON, Canada N0C 1H0
EDITOR—I write with reference to the paper by Fergusson et al.1 Asking patients or their clinicians at the end of a trial which drug they think they were taking confounds failures in blinding with successes in pre-trial hunches about efficacy.
Thirty years ago, at the end of the first ever trial of aspirin and sulfinpyrazone …
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