- Sarah J O'Brien, head of gastrointestinal diseases division (sarah.o'brien@hpa.org.uk),
- Roger A Feldman, emeritus professor of clinical epidemiology
- Health Protection Agency, Communicable Disease Surveillance Centre, London NW9 5EQ
- Barts and the London, Queen Mary School of Medicine and Dentistry, University of London E1 2AD
EDITOR—The article by Helms et al raises the importance of case selection and clinical data on the estimates of short and long term mortality from clinical illness.1 Clinicians' understanding of an illness entails identifying symptoms and signs, in relation to age, sex, and geography, the three variables for which the authors selected controls. But clinicians also decide on the necessity for diagnostic laboratory tests. Results deemed …
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