- DouglasG Altman, professor of statistics in medicine,
- KennethF Schulz, vice president of quantitative sciences,
- David Moher, director
- Cancer Research UK Medical Statistics Group, Centre for Statistics in Medicine, Institute of Health Sciences, Oxford OX3 7LF doug.altman@cancer.org.uk
- Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA
- Chalmers Research Group, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada K1H 8L1
EDITOR—Several correspondents have criticised the HOPE investigators for focusing on relative effects when the absolute benefit was very small. Twisselmann, in her summary of many responses on the website, comments: “It was noted that only the relative risk reduction was given in the study. This should have been accompanied by data on absolute risk reduction and number needed to treat and even number needed to harm (as per CONSORT guidelines).”1
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