Effect of temazepam on ventilatory response at moderate altitude

BMJ 2000; 320 doi: 10.1136/bmj.320.7226.56 (Published 1 January 2000)
Cite this as: BMJ 2000;320:56.1

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  1. Georg Röggla, head of department (interne@khneunkirchen.at),
  2. Berthold Moser, student,
  3. Martin Röggla, lecturer
  1. Department of Internal Medicine, Municipal Hospital of Neunkirchen, Neunkirchen, Austria
  2. Department of Emergency Medicine, University of Vienna, Austria

    EDITOR—Dubowitz's study of the effect of temazepam on oxygen saturation at high altitude found that benzodiazepines do not have a depressant effect.1 He explains the discrepancy between his findings and those of previous studies by the fact that other studies have investigated the effect of long acting benzodiazepines.2 Dubowitz's probands were investigated after altitude acclimatisation while walking to Everest base camp, whereas climbers in Europe mainly engage in short periods of mountaineering. We therefore evaluated the effect of 10 mg temazepam on respiration in …

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