EDITOR,--John A Henry and colleagues draw several familiar conclusions from their study of suicide and antidepressants.1 They argue that their data “provide a useful guide to the relative toxicities of drugs and an indication of the needs for prescribing policy” and suggest that a considerable number of suicides could be prevented by a switch to routine prescribing of selective serotonin reuptake inhibitors. This opinion is not always expressed in such restrained terms--as the accompanying editorial reminds us2--and yet it is based on two unproved assumptions. The first is that relative mortality due to overdose is the same …