Letter
Acute renal failure associated with NSAIDS
Cite this as:
BMJ
1994;308:857.5
- C A O'Callaghan
- Renal Unit, Guy's Hospital, London SE1 9RT.
Editor,--G W Smith and S B Cohen report on a 79 year old woman who was taking non-steroidal anti-inflammatory drugs and developed renal impairment and hyperkalaemia when a urinary tract infection was treated with trimethoprim.1 They unreasonably dismiss the non-steroidal anti-inflammatory drug as a possible cause of the renal disease.
Non-steroidal anti-inflammatory drugs inhibit the normal tonic renal vasodilatation induced by prostaglandin. Loss of this …
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